QOPEVSAlpha Sophia

QOPE vs Alpha Sophia for U.S. provider research

Alpha Sophia is a healthcare commercial intelligence platform built on claims data. QOPE is a self-serve platform built on public CMS, FDA, HRSA, NIH and ONC data, covering providers, facilities and drugs.

Information as of October 7, 2026Start 14-day trialSee pricing
Side by side

Where the two overlap

Provider search, provider profiles and matching your own lists to NPIs. Facts about Alpha Sophia come from its own website, with a source link on each row.

What it is
QOPEA self-serve platform that turns public U.S. healthcare data into ranked answers, drug and provider profiles, lead lists and watch lists.
Alpha SophiaDescribes itself as a healthcare commercial intelligence platform for life sciences and healthcare organizations of every size.Source
Built for
QOPEAnalysts, consultants, investors and commercial teams who work with U.S. drug, provider and facility data.
Alpha SophiaLists pharma, biotech, MedTech, healthcare providers, hospitals and ambulatory surgery centers, health insurers and research institutions.Source
Data
QOPE28 datasets in 6 groups (Providers, Facilities, Access, Trials, Drugs, Research), built from public CMS, FDA, HRSA, NIH and ONC data. Provider activity comes from Medicare Part B and Part D files (data year 2024).
Alpha SophiaLists 3.9M+ providers and insights from about 80% of U.S. medical claims (300M+ patient lives) from Medicare, Medicaid, government and commercial payors.Source 1Source 2
Main tools
QOPEInsights, provider profiles and compare, Drug Profile, Patent Cliff, Map, Lead Lists, NPI Match and Radar.
Alpha SophiaProvider targeting and profiles, Referral Intelligence, Bulk NPI Lookup, and an in-app assistant with access for outside AI agents over the Model Context Protocol.Source 1Source 2Source 3
Contact details
QOPEPractice address and phone from NPPES and the CMS NPI Registry.
Alpha SophiaProvider profiles include contact information.Source
Getting access
QOPESelf-serve sign-up with a 14-day trial. No sales call needed.
Alpha SophiaBook a demo from its website.Source
Pricing
QOPEPublished prices: Regular $450, Pro $1,250, Teams $4,750 per month, with lower annual prices.
Alpha SophiaTwo plans, Max and Custom, both priced on request. Max includes 5 users.Source
What you can do on QOPE

Four views for provider research

Each one is a prepared view, so you start from an answer instead of an empty table.

01 / INSIGHTS

Ranked answers in one click

Insights answers questions such as who prescribes a drug the most, ranked by Part D drug cost and filtered by state and specialty. Each row opens its record page.

How Insights works
Provider search filtered by location, specialty and affiliation
02 / PROVIDER PROFILE

One page per provider

Procedures, prescribing, chronic-condition prevalence, Open Payments, similar providers and shortage-area context for each NPI. Compare up to four providers side by side.

See record pages
Drug, facility, market and location sources feeding one provider dossier
03 / NPI MATCH

Match your own list to NPIs

Upload a CSV or Excel list of names, up to 500 rows per run. NPI Match checks each row against the CMS NPI Registry, shows the candidates and saves the matches as a lead list. Pro and Teams plans.

How NPI Match works
Uploaded provider list is matched against the NPI registry, producing verified matches
04 / DRUG PROFILE

One page per drug

Patents and exclusivity, generic and biosimilar makers, NADAC price, shortages, recalls, top Part D prescribers and Part B spend for each drug, with an Excel export.

How the drug profile works
Drug profile for apixaban with KPI strip, patent and exclusivity timeline, price trend and Excel export
Which one fits

Pick by the question you need answered

Both are useful. They answer different questions.

QOPE may fit better when
  • You research U.S. providers and also need drug, patent and shortage data.
  • You want to start today, without a sales call, at a published price.
  • You want to match your own list of names to NPIs and save it as a lead list.
  • You want the public source of each dataset named next to it.
Alpha Sophia may fit better when
  • You need all-payer procedure and patient volumes, not Medicare files alone.
  • You need referral patterns between providers.
  • You want an AI assistant, or to query the data from your own AI agent.
Questions

Common questions

Does QOPE have all-payer claims?

No. QOPE provider activity comes from public Medicare Part B and Part D files, data year 2024.

Can QOPE match my own list of providers?

Yes. NPI Match takes a CSV or Excel list of names, up to 500 rows per run, checks each row against the CMS NPI Registry and saves the matches as a lead list. It is on the Pro and Teams plans.

Can I try QOPE without talking to sales?

Self-serve sign-up with a 14-day trial. No sales call needed.

How much does QOPE cost?

Published prices: Regular $450, Pro $1,250, Teams $4,750 per month, with lower annual prices.

Try it on your own question

Search a drug, a provider or a market today.

Regular$450/mo
Pro$1,250/mo
Teams$4,750/mo
One search across databases, documents, facilities and drugs