Drug facts
MoleculeTrazodone
Generics already compete: 12 makers on the market. 40 A-rated products from 12 makers substitute at the counter.
Desyrel was first approved by the FDA before 1982 under NDA 018207; the application holder is Pragma Pharmaceuticals LLC. The Orange Book lists NDA 018207 as discontinued.
The latest NADAC for TRAZODONE 100 MG TABLET is $0.05 per unit (as of 10/28/2026).
Holder Pragma Pharmaceuticals LLCApplication NDA 018207Approved before 1982
01Patents and exclusivity
When competition can legally begin. A generic can launch once both exclusivity and the last listed patent expire, unless a court or settlement says otherwise.
- Latest patent
- 03/13/2029Desyrel Orange Book
02Competition
- Generics
- 12 generic makers Orange Book
- First generic approved
- 10/10/1986 Orange Book
Every listingEach listing and maker behind the generics count.
Price erosionHow NADAC moves as generics enter.
PrescribersWho prescribes it, from Medicare data.
Available in the full Trazodone profile.See what is included
03Supply and price
- FDA drug shortage
- ClearNot on the current shortage list FDA shortages
- NADAC
- $0.05 per unitTRAZODONE 100 MG TABLET, mid-priced of 4 strengths, as of 10/28/2026 CMS NADAC
- Latest recall
- 08/24/2026Class II, Trazodone Hydrochloride, Teva Pharmaceuticals USA, Inc FDA enforcement
04Product
- Application holder
- Pragma Pharmaceuticals LLC Orange Book
- Application
- NDA 018207 Orange Book
- First approved
- before 1982 Orange Book
- Dosage forms
- solution; tablet
- Routes
- oral
- Other brand names
- Raldesy
- Status
- NDA 018207 discontinued Orange Book
Sources: FDA Orange Book, FDA Purple Book, FDA drug shortages, FDA enforcement reports and CMS NADAC, read through QOPE. Not medical or legal advice.