Drug facts
MoleculeMetoprolol Succinate (Toprol-XL)
Generics already compete: 17 makers on the market. 60 A-rated products from 17 makers substitute at the counter.
Toprol-XL was first approved by the FDA on 01/10/1992 under NDA 019962; the application holder is Melinta Therapeutics LLC A Wholly Owned Sub of Cormedix Inc.
The latest NADAC for METOPROLOL SUCC ER 50 MG TAB is $0.05 per unit (as of 10/28/2026).
Holder Melinta Therapeutics LLC A Wholly Owned Sub of Cormedix IncApplication NDA 019962Approved 01/10/1992
01Patents and exclusivity
When competition can legally begin. A generic can launch once both exclusivity and the last listed patent expire, unless a court or settlement says otherwise.
- Latest patent
- No Toprol-XL patent listed in the Orange Book Orange Book
- Later patents, other products
- Kapspargo Sprinkle 07/09/2035 Orange Book
02Competition
- Generics
- 17 generic makers Orange Book
- First generic approved
- 07/31/2006 Orange Book
Every listingEach listing and maker behind the generics count.
Price erosionHow NADAC moves as generics enter.
PrescribersWho prescribes it, from Medicare data.
Available in the full Metoprolol Succinate profile.See what is included
03Supply and price
- FDA drug shortage
- ClearNot on the current shortage list FDA shortages
- NADAC
- $0.05 per unitMETOPROLOL SUCC ER 50 MG TAB, mid-priced of 4 strengths, as of 10/28/2026 CMS NADAC
- Latest recall
- 04/27/2026Class II, Ascend Laboratories, Ascend Laboratories, LLC FDA enforcement
04Product
- Application holder
- Melinta Therapeutics LLC A Wholly Owned Sub of Cormedix Inc Orange Book
- Application
- NDA 019962 Orange Book
- First approved
- 01/10/1992 Orange Book
- Dosage forms
- capsule, extended release; tablet, extended release
- Routes
- oral
- Other brand names
- Kapspargo Sprinkle
Sources: FDA Orange Book, FDA Purple Book, FDA drug shortages, FDA enforcement reports and CMS NADAC, read through QOPE. Not medical or legal advice.