Drug facts
MoleculeCiprofloxacin (Cipro)
Generics already compete: 15 makers on the market. 33 A-rated products from 15 makers substitute at the counter.
Cipro was first approved by the FDA on 10/22/1987 under NDA 019537; the application holder is Bayer Healthcare Pharmaceuticals Inc.
The latest NADAC for CIPROFLOXACIN HCL 500 MG TAB is $0.12 per unit (as of 10/28/2026).
Holder Bayer Healthcare Pharmaceuticals IncApplication NDA 019537Approved 10/22/1987
01Patents and exclusivity
When competition can legally begin. A generic can launch once both exclusivity and the last listed patent expire, unless a court or settlement says otherwise.
- Latest patent
- No Cipro patent listed in the Orange Book Orange Book
02Competition
- Generics
- 15 generic makers Orange Book
- First generic approved
- 06/09/2004 Orange Book
Every listingEach listing and maker behind the generics count.
Price erosionHow NADAC moves as generics enter.
PrescribersWho prescribes it, from Medicare data.
Available in the full Ciprofloxacin profile.See what is included
03Supply and price
- FDA drug shortage
- ClearNot on the current shortage list FDA shortages
- NADAC
- $0.12 per unitCIPROFLOXACIN HCL 500 MG TAB, mid-priced of 3 strengths, as of 10/28/2026 CMS NADAC
- Latest recall
- 03/11/2025Class II, Ciprofloxacin, Fdc Limited FDA enforcement
04Product
- Application holder
- Bayer Healthcare Pharmaceuticals Inc Orange Book
- Application
- NDA 019537 Orange Book
- First approved
- 10/22/1987 Orange Book
- Dosage forms
- ointment; solution/drops; tablet
- Routes
- ophthalmic, oral, otic
- Other brand names
- CetraxalCiloxan
Sources: FDA Orange Book, FDA Purple Book, FDA drug shortages, FDA enforcement reports and CMS NADAC, read through QOPE. Not medical or legal advice.