Drug facts
MoleculeAllopurinol (Zyloprim)
Generics already compete: 12 makers on the market. 27 A-rated products from 12 makers substitute at the counter.
Zyloprim was first approved by the FDA before 1982 under NDA 016084; the application holder is Casper Pharma LLC.
The latest NADAC for ALLOPURINOL 300 MG TABLET is $0.05 per unit (as of 10/28/2026).
Holder Casper Pharma LLCApplication NDA 016084Approved before 1982
01Patents and exclusivity
When competition can legally begin. A generic can launch once both exclusivity and the last listed patent expire, unless a court or settlement says otherwise.
- Latest patent
- No Zyloprim patent listed in the Orange Book Orange Book
02Competition
- Generics
- 12 generic makers Orange Book
- First generic approved
- 12/10/1985 Orange Book
Every listingEach listing and maker behind the generics count.
Price erosionHow NADAC moves as generics enter.
PrescribersWho prescribes it, from Medicare data.
Available in the full Allopurinol profile.See what is included
03Supply and price
- FDA drug shortage
- ClearNot on the current shortage list FDA shortages
- NADAC
- $0.05 per unitALLOPURINOL 300 MG TABLET, mid-priced of 3 strengths, as of 10/28/2026 CMS NADAC
- Latest recall
- 06/07/2024Class II, Allopurinol, Dr. Reddy's Laboratories, Inc. FDA enforcement
04Product
- Application holder
- Casper Pharma LLC Orange Book
- Application
- NDA 016084 Orange Book
- First approved
- before 1982 Orange Book
- Dosage forms
- tablet
- Routes
- oral
- Other brand names
- Lopurin
Sources: FDA Orange Book, FDA Purple Book, FDA drug shortages, FDA enforcement reports and CMS NADAC, read through QOPE. Not medical or legal advice.